Thomas Smith

Thomas Smith

Company: Novartis

Job title: Senior Investigator

Bio:

Thomas Smith earned a MA and PhD in biological sciences at the University at Buffalo, NY and completed post-doctoral studies at the University of Cincinnati College of Medicine, OH in cell pharmacology and biophysics.  In 2001, Dr. Smith joined the scientific staff in the Department of Cardiovascular and Metabolic Diseases at Genetics Institute / Wyeth Research in Cambridge, MA focusing on platelet biology and therapies for cardiovascular diseases, before joining the Novartis Institutes for Biomedical Research in Cambridge, MA in 2007.  In his current role in the department of Chemical Biology and Therapeutics at Novartis, Dr. Smith works with project teams from multiple disease areas to enable early stage drug discovery efforts on new programs of therapeutic interest.  He is co-author or inventor on over 30 publications and patents.

Seminars:

Discussion/Q&A 12:10 pm

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day: Day Two

Discussion/Q&A 10:00 am

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day: Day Two

Discussion/Q&A 12:20 pm

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day: Day One

Chair’s Opening Remarks 8:50 am

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day: Day Two

Finding the Needle in the Haystack: Learnings in Integrated Lead Discovery 11:40 am

No single assay will find all of the hits, all of the time, so how does one pick the “right” assay for a new lead discovery campaign? Robust identification and characterization of chemical starting points requires well-validated and predictive biochemical, biophysical, and cellular assays There are significant benefits in combining multiple screening approaches, whether concurrently…Read more

day: Day One

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