Company: Silicon Therapeutics
Job title: Senior Director of Medicinal Chemistry & Computational Design
Steve is a highly experienced medicinal chemist and molecular designer with over 10 years of project leadership experience across several therapeutic areas and a proven record of advancing molecules through early hit-to lead phases into late stage preclinical / IND enabling studies. Throughout his career Steve has become an industry recognized expert in SBDD with extensive experience in applying computational tools to supporting new compound design and project decision making. Steve joined Silicon Therapeutics from Takeda Pharmaceuticals (San Diego, CA), where he was Associate Director of Chemistry and lead a team of 8 chemists and 2 computational scientists who supported projects across the portfolio. Prior to Takeda, he spent 6 years in the medicinal chemistry groups at Eli Lilly and Abbvie where he gained unique experience in the early stages of drug discovery including: FBDD, novel approaches to hit ID and lead optimization, efficiency metrics, as well computational modeling and SBDD across different target classes. His research experience covers gastroenterology, immuno-oncology, inflammation, and autoimmune diseases. Steve obtained and dual B.S in Biology and Chemistry and received his PhD from the University of Delaware working for John Koh.