Job title: Senior Director of Chemical Biology & Proteomics
Douglas Johnson is a Senior Director of Chemical Biology & Proteomics at Biogen in Cambridge, MA. Prior to moving to Biogen, Doug was at Pfizer for 18 years where his most recent position was Senior Scientific Director and Head of Chemical Biology in Cambridge, MA. Prior to Pfizer, Doug was an NIH postdoctoral fellow at Harvard University in the laboratory of Professor David A. Evans. He obtained his Ph.D. in organic chemistry at The Scripps Research Institute under the guidance of Professor Dale L. Boger and graduated summa cum laude from the University of Minnesota with a BS in chemistry. He is an author or inventor on more than 90 publications and patents.
Application of Chemical Biology Probes and Bioorthogonal Chemistry in Drug Discovery 9:00 am
Several examples of how chemical biology probes and bioorthogonal chemistry were used for target identification and engagement, selectivity profiling (offtargets) and mechanism of action studies in drug discovery projects Several different types of chemical biology probes were utilized including enzyme class-specific activity-based probes, cysteine-specific reactivity-based probes as well as target-specific clickable covalent inhibitor and photoaffinity…Read more
day: Day One